Interval hypoxic training as the method of rehabilitation of patients with cardiovascular diseases: A literature review



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Abstract

Ensuring full restoration of the functional capabilities of the body is the main task of medical rehabilitation. The introduction of new methods of patient rehabilitation into clinical practice allows achieving significant success in the treatment and prevention of diseases, which may be associated with greater efficiency of specific methods, simplicity and safety of their use, which increases patient compliance, and their economic availability. Recently, the effect of interval hypoxia (IH) on the human body has attracted increasing interest. The mechanisms by which clinically significant effects of interval hypoxic training (IHT) are realized have been described at various levels - from the regulation of gene expression to systemic physiological reactions. Interval hypoxic training is a method that has found application in the prevention and treatment of a number of chronic non-infectious diseases of the cardiovascular, respiratory and nervous systems, endocrinological pathologies, and has an effect on the course of inflammation and aging processes. IHT can be used both at rest and during physical activity, which made it possible to use this method in sports medicine. In the last decade, a method alternating the effects of periods of hypoxia and hyperoxia on the body has been actively developed. There are suggestions that replacing periods of normoxia with hyperoxic ones can lead to an increase in the effectiveness of IHT and a decrease in negative side effects. This article provides an overview of information available in domestic and foreign literature concerning the mechanisms of the effects of IHT on the human body and the possibilities of their use in cardiovascular pathology.

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About the authors

Aleksandr K. Nagovitsin

N.N. Burdenko Voronezh State Medical University

Author for correspondence.
Email: nagovizinak@gmail.com
ORCID iD: 0000-0002-2452-1105
SPIN-code: 3024-7503

assistant of the Department of Clinical Laboratory Diagnostics

Russian Federation, 394036, Voronezh, ul. Studencheskaya, 10

Yuliya A. Kotova

N.N. Burdenko Voronezh State Medical University

Email: kld@vrngmu.ru
ORCID iD: 0000-0003-0236-2411
SPIN-code: 8518-0355

Doct. Sci. (Med.), Associate Professor, Head of the Department of Clinical Laboratory Diagnostics

Russian Federation, 394036, Voronezh, ul. Studencheskaya, 10

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