CardioSomaticsCardioSomaticsCardioСоматика2221-71852658-5707Eco-Vector4504610.26442/CS45046ArticlesСтатьиResearch ArticleCalcium antagonist lercanidipine in hypertensionАнтагонист кальция лерканидипин при артериальной гипертензииBaryshnikovaG. AБарышниковаГалина Анатольевна

д-р мед. наук, проф. каф. семейной медицины ФГБУ УНМЦ УД Президента РФ

ChorbinskayaS. AЧорбинскаяСветлана Алексеевна

д-р мед. наук, проф., зав каф. семейной медицины ФГБУ УНМЦ УД Президента РФ

StepanovaI. IСтепановаИрина Ираклиевна

канд. мед. наук, доц. каф. семейной медицины ФГБУ УНМЦ УД Президента РФ

Educational Research Medical Center, Office of the President of the Russian FederationФГБУ Учебно−научный медицинский центр Управления делами Президента Российской Федерации1503201451NO1 (2014)ТОМ 5, №1 (2014)91524092020Copyright ©; 2014, Eco-VectorCopyright ©; 2014, ООО "Эко-Вектор"2014Eco-VectorООО "Эко-Вектор"https://creativecommons.org/licenses/by-nc-sa/4.0https://cardiosomatics.ru/2221-7185/article/view/45046

The article presents the results of studies on the effectiveness and safety of a III generation calcium antagonist lercanidipine in the treatment of hypertension. Lercanidipine treatment leads to a marked significant reduction in systolic and diastolic blood pressure without producing a significant effect on heart rate. The drug has organ-protective effect, reduces left ventricular hypertrophy, improves kidney function and has antiproteinuric action. Lercanidipine is well tolerated, less likely to cause peripheral edema compared with other calcium antagonists.

В статье представлены результаты исследований по изучению эффективности и безопасности антагониста кальция III поколения лерканидипина в лечении артериальной гипертензии. Лечение лерканидипином приводит к выраженному достоверному снижению систолического и диастолического артериального давления без существенного влияния на частоту сердечных сокращений. Препарат обладает органопротективным действием, уменьшает гипертрофию левого желудочка, улучшает функцию почек и оказывает антипротеинурическое действие. Лерканидипин хорошо переносится, реже вызывает периферические отеки по сравнению с другими антагонистами кальция.

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