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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">CardioSomatics</journal-id><journal-title-group><journal-title xml:lang="en">CardioSomatics</journal-title><trans-title-group xml:lang="ru"><trans-title>CardioСоматика</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2221-7185</issn><issn publication-format="electronic">2658-5707</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">45164</article-id><article-id pub-id-type="doi">10.26442/CS45164</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Therapeutic effects of fosinopril - ACE inhibitor</article-title><trans-title-group xml:lang="ru"><trans-title>Терапевтические эффекты ингибитора ангиотензинпревращающего фермента фозиноприла</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Aronov</surname><given-names>D. M</given-names></name><name xml:lang="ru"><surname>Аронов</surname><given-names>Давид Меерович</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, проф., засл. деятель науки РФ, рук. лаб. кардиореабилитации ФГБУ ГНИЦ ПМ</p></bio><email>aronovdm@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">State Research Center for Preventive Medicine of the Ministry of Health of the Russian Federation</institution></aff><aff><institution xml:lang="ru">ФГБУ Государственный научно-исследовательский центр профилактической медицины Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2015-06-15" publication-format="electronic"><day>15</day><month>06</month><year>2015</year></pub-date><volume>6</volume><issue>2</issue><issue-title xml:lang="en">NO2 (2015)</issue-title><issue-title xml:lang="ru">ТОМ 6, №2 (2015)</issue-title><fpage>56</fpage><lpage>63</lpage><history><date date-type="received" iso-8601-date="2020-09-24"><day>24</day><month>09</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2015, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2015, ООО "Эко-Вектор"</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">ООО "Эко-Вектор"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://cardiosomatics.ru/2221-7185/article/view/45164">https://cardiosomatics.ru/2221-7185/article/view/45164</self-uri><abstract xml:lang="en"><p>The review article dials with the characteristics of fosinopriltherapeutic features, apparently associated with the fact that it contains phosphorus. It has special specter possessing the numerous of organotropic effects and good tolerability and safety, allowing tochange the drug tofosinoprilin patients,who has dry cough, and have been treated using different ACE inhibitors. We discuss the possible prospects of drugs appointment in case of unconventional diseasesfor ACE inhibitors application.</p></abstract><trans-abstract xml:lang="ru"><p>В обзорной статье дается характеристика терапевтических особенностей фозиноприла, по-видимому, связанных с тем, что он содержит фосфор. У препарата многочисленный ярко выраженный спектр органотропных эффектов и очень хорошая переносимость и безопасность, позволяющие переводить больных (леченных разными ингибиторами ангиотензинпревращающего фермента), у которых развился сухой кашель, на лечение фозиноприлом. Обсуждаются возможные перспективы применения препарата при нетрадиционной для ингибиторов ангиотензинпревращающего фермента патологии.</p></trans-abstract><kwd-group xml:lang="en"><kwd>ACE inhibitors</kwd><kwd>fosinopril</kwd><kwd>monopril</kwd><kwd>chronic cardiac failure</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>ингибиторы ангиотензинпревращающего фермента</kwd><kwd>фозиноприл</kwd><kwd>моноприл</kwd><kwd>хроническая сердеч-ная недостаточность</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Borghi C, Marino P, Zardini P et al. Post acute myocardial infarction: the Fosinopril in Acute Myocardial Infarction Study (FAMIS). Am J Hypertens 1997; 10 (10 Pt. 2): 247S-254S.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Konermann M, Qdenthal H.J, Altmann C et al. Effect of ACE-inhibitors on left ventricular remodeling after acute anterior or posterior myocardial infarct. 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