<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE root>
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">CardioSomatics</journal-id><journal-title-group><journal-title xml:lang="en">CardioSomatics</journal-title><trans-title-group xml:lang="ru"><trans-title>CardioСоматика</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2221-7185</issn><issn publication-format="electronic">2658-5707</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">45264</article-id><article-id pub-id-type="doi">10.26442/CS45264</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Current representation of endovascular treatment of patients with left main coronary artery disease</article-title><trans-title-group xml:lang="ru"><trans-title>Современные подходы к стентированию ствола левой коронарной артерии</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Vlasov</surname><given-names>V. Yu</given-names></name><name xml:lang="ru"><surname>Власов</surname><given-names>В. Ю</given-names></name></name-alternatives><email>avrelliy@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Rudenko</surname><given-names>B. A</given-names></name><name xml:lang="ru"><surname>Руденко</surname><given-names>Б. А</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, вед. науч. сотр. лаб. рентгенэндоваскулярных методов диагностики и лечения ФГБУ ГНИЦ ПМ</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Shanoyan</surname><given-names>A. S</given-names></name><name xml:lang="ru"><surname>Шаноян</surname><given-names>А. С</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук, зав. отд-нием рентгенхирургических методов диагностики и лечения ФГБУ ГНИЦ ПМ</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Mazaev</surname><given-names>V. P</given-names></name><name xml:lang="ru"><surname>Мазаев</surname><given-names>В. П</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, рук. лаб. рентгенэндоваскулярных методов диагностики и лечения ФГБУ ГНИЦ ПМ</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Akhadova</surname><given-names>A. Sh</given-names></name><name xml:lang="ru"><surname>Ахадова</surname><given-names>А. Ш</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач 1-го кардиологического отд-ния ФГБУ ГНИЦ ПМ</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Shukurov</surname><given-names>F. B</given-names></name><name xml:lang="ru"><surname>Шукуров</surname><given-names>Ф. Б</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач рентгенэндоваскулярных методов диагностики и лечения ФГБУ ГНИЦ ПМ</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">State Research Center for Preventive Medicine of the Ministry of Health of the Russian Federation</institution></aff><aff><institution xml:lang="ru">ФГБУ Государственный научно-исследовательский центр профилактической медицины Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2016-06-15" publication-format="electronic"><day>15</day><month>06</month><year>2016</year></pub-date><volume>7</volume><issue>2</issue><issue-title xml:lang="en">VOL 7, NO2 (2016)</issue-title><issue-title xml:lang="ru">ТОМ 7, №2 (2016)</issue-title><fpage>56</fpage><lpage>59</lpage><history><date date-type="received" iso-8601-date="2020-09-24"><day>24</day><month>09</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2016, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2016, ООО "Эко-Вектор"</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">ООО "Эко-Вектор"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://cardiosomatics.ru/2221-7185/article/view/45264">https://cardiosomatics.ru/2221-7185/article/view/45264</self-uri><abstract xml:lang="en"><p>Coronary artery bypass grafting (CABG) is known as the gold standard treatment of unprotected left main coronary artery (LMCA) disease and has the highest level of evidence in European and American recommendations. However development of endovascular methods of treatment, and first of all decrease of in-stent-restenosis allow us to consider angioplasty and stenting of LMCA as an alternative method to CABG. The comparative world analysis of results of percutaneous coronary interventions and CABG is provided in article. It tells also how efficiency of percutaneous coronary interventions depends on such factors as lesion localization, diabetes, type of drug-eluting stent.</p></abstract><trans-abstract xml:lang="ru"><p>Операция коронарного шунтирования является «золотым стандартом» реваскуляризации миокарда при поражениях ствола левой коронарной артерии и имеет наивысший уровень доказательности в европейских и американских рекомендациях. Однако развитие эндоваскулярных методов лечения, и в первую очередь снижение внутристентового рестеноза, способствует рассмотрению ангиопластики со стентированием ствола левой коронарной артерии как альтернативы коронарному шунтированию. В статье приводится сравнительный мировой анализ результатов чрескожного коронарного вмешательства и аортокоронарного шунтирования у данной категории пациентов, а также анализируется эффективность эндоваскулярного метода лечения при наличии таких влияющих на прогноз факторов, как локализация поражения, сахарный диабет, тип антипролиферативного покрытия стента.</p></trans-abstract><kwd-group xml:lang="en"><kwd>left main coronary artery disease</kwd><kwd>percutaneous coronary interventions</kwd><kwd>coronary artery bypass grafting</kwd><kwd>angioplasty and stenting</kwd><kwd>endovascular methods of treatment</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>поражение ствола левой коронарной артерии</kwd><kwd>чрескожные коронарные вмешательства</kwd><kwd>операция коронарного шунтирования</kwd><kwd>ангиопластика со стентированием</kwd><kwd>эндоваскулярные методы лечения</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Mehta J, Hamby R, Hoffman G. Medical - surgical aspects of left main coronary disease. J Thorac Cardiovasc Surg 1976; 71 (1): 137-41.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Proudfit W.L, Bruschke A.V.G, Stones F.M. Natural history of obstructive coronary artery disease: ten - year study of 601 nonsurgical cases. Prag Cardiovasc Dis 1978; 21: 53-78.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Taylor H, Deumite N, Chaitman B et al. Asymptomatic left main coronary artery disease in the Coronary Artery Surgery Study (CASS) registry. Circulation 1989; 79: 1171-9.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Cohen M.V, Gorlin R. Main left coronary artery disease. Clinical experience from 1964-1974. Circulation 1975; 52: 275-85.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Saint-Pierre A, Amiel M, Jamet C et al. Significance of atheromatous stenoses of common trunk of the left coronary artery. Arch Mal Coeur Vaiss 1974; 67 (11): 1305-15.</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Lee M.S, Kapoor N, Jamal F et al. Comparison of coronary artery bypass surgery with percutaneous coronary intervention with drug - eluting stents for unprotected left main coronary artrery disease. J Am Coll Cardiol 2006; 47: 864-70.</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Hill R, Bagust A, Bakhai A, Dickson R et al. Coronary artery stents: a rapid systematic review and economic evaluation. Health Technol Assess 2004; 8: 1-242.</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Smith S.C et al. ACC/AHA/SCAI 2005 guideline update for percutaneous coronary intervention: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (ACC/AHA/SCAI Writing Committee to Update the 2001 Guidelines for Percutaneous Coronary Intervention). J Am Coll Cardiol 2006; 47 (1): 1-121.</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>Савченко А.П., Черкавская О.В., Руденко Б.А., Болотов П.А. Интервенционная кардиология. М.: ГЭОТАР-Медиа, 2010; с. 253-66.</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>O’Keefe J.H Jr, Hartzler G.O, Rutherford B.D et al. Left nain coronary angioplasty: early and late results of 127 acute and elective procedures. Am J Cardiol 1989; 64: 144-7.</mixed-citation></ref><ref id="B11"><label>11.</label><mixed-citation>Sabik J.F, Blackstone E.H, Firstenberg M, Lytle B.W. A benchmark for evaluation innovative treatment of left main coronary disease. Circulation 2007; 116 (Suppl.): 232-9.</mixed-citation></ref><ref id="B12"><label>12.</label><mixed-citation>Tan W.A, Tamai H, Park S.J et al. Long - term clinical outcomes after unprotected left main trunk percutaneous revascularization in 279 patients. Circulation 2001; 104 (14): 1609-14.</mixed-citation></ref><ref id="B13"><label>13.</label><mixed-citation>Boccalatte M, Sousa P, Ali H, Hasan H et al. Unprotected left main coronary stenting: Long - and medium - term outcomes. Am J Cardiol 2001; 88: 4-6 (Suppl. 1).</mixed-citation></ref><ref id="B14"><label>14.</label><mixed-citation>Kosuga K, Tamai H, Ueda K et al. Initial and long - term results of angioplasty in unprotected left main coronary artery. Am J Cardiol 1999; 83 (1): 32-7.</mixed-citation></ref><ref id="B15"><label>15.</label><mixed-citation>Kim Y.H, Park D.W, Lee S.W et al. Long - term safety and effectiveness of unprotected left main coronary stenting with drug - eluting stents compared with bare - metal stents. Circulation 2009; 120: 400-7.</mixed-citation></ref><ref id="B16"><label>16.</label><mixed-citation>Palmerini T, Marzocchi A, Tamburino C et al. Two - year clinical outcome with drug - eluting stents versus bare - metal stents in a real - world registry of unprotected left main coronary artery stenosis from the Italian Society of Invasive Cardiology. Am J Cardiol 2008; 102: 1463-8.</mixed-citation></ref><ref id="B17"><label>17.</label><mixed-citation>Park S.L, Kim Y.H. Sirolimus - eluting stent implantation for unprotected left main coronary artery stenosis: Comparison with bare metal stent implantation. J Am Coll Cardiol 2005; 45: 351-6.</mixed-citation></ref><ref id="B18"><label>18.</label><mixed-citation>Morice M.C, Serruys P.W, Kappetein A.P et al. Outcomes in patients with de novo left main disease treated with either percuyaneous coronary intervention using paclitaxel - eluting stents or coronary artery bypass graft treatment in the Synergy Between Percutaneous Coronary Intervention with TAXUS and Cardiac Surgery (SYNTAX) trial. Circulation 2010: 121 (24): 2645-53.</mixed-citation></ref><ref id="B19"><label>19.</label><mixed-citation>Morice M.C, Serruys P.W, Kappetein A.P et al. Five-Year Outcomes in Patients with Left Main Desease Treated with Either Percutaneous Coronary Intervention or Coronary Artery Bypass Grafting in the SYNTAX trial. Circulation 2014; 129: 2388-94.</mixed-citation></ref><ref id="B20"><label>20.</label><mixed-citation>Windecker S, Kolh Ph, Alfonso F et al. 2014 ESC/EACTS Guidelines on myocardial revascularization. Eur Heart J 2014.</mixed-citation></ref><ref id="B21"><label>21.</label><mixed-citation>Park D.W, Kim Y.H, Yun S.C et al. Long - term outcomes after stenting vs. coronary artery bypass grafting for unprotected left main coronary artery disease: 10-year results of bare - metal stents and 5-year results of drug - eluting stents from the ASAN-MAIN (ASAN Medical Center - Left MAIN Revascularization) Registry. J Am Coll Cardiol 2010; 56 (17): 1366-75.</mixed-citation></ref><ref id="B22"><label>22.</label><mixed-citation>Ahn J.M, Roh J.H, Kim Y.H et al. Randomized trial of stents versus bypass surgery for left main coronary artery disease: Five - year outcomes of the PRECOMBAT study. J Am Coll Cardiol 2015; doi:10.1016/j.jacc.2015.03.033</mixed-citation></ref><ref id="B23"><label>23.</label><mixed-citation>Chen S.L et al. Distal left main coronary bifurcation lesion predict worse outcome in patients undergoing percutaneous implantation of drug - eluting stents: results from the Drug-Eluting Stent for the Treatment of Left Main Disease (DISTAL) study. Cardiology 2009; 113 (4): 264-73.</mixed-citation></ref><ref id="B24"><label>24.</label><mixed-citation>Niemela M, Kervinen K, Erglis A et al. Randomized comparison of final kissing balloon dilatation versus no final kissing balloon dilatation in patients with coronary bifurcation lesions treated with main vessel stenting: the Nordic - Baltic Bifurcation Stude III. Circulation 2011; 123 (1): 79-86.</mixed-citation></ref><ref id="B25"><label>25.</label><mixed-citation>Farkouh M.E, Domanski M, Sleeper L.A et al. Strategies for multivessel revascularization in patients with diabetes. N Engl J Med 2012; 367: 2375-84.</mixed-citation></ref><ref id="B26"><label>26.</label><mixed-citation>Акчурин Р.С., Власова Э.Е., Мершин К.В. Сахарный диабет и хирургическое лечение ишемической болезни сердца. Вестн. РАМН. 2012; 1: 14-9.</mixed-citation></ref><ref id="B27"><label>27.</label><mixed-citation>Raber L, Juni P, Nuesch E et al. Long - term comparison of everolimus - eluting and sirolimus - eluting stents for coronary revascularization. J Am Coll Cardiol 2011; 57: 2143-51.</mixed-citation></ref><ref id="B28"><label>28.</label><mixed-citation>Mehilli J, Richardt G, Valgimigli M et al. Zotarolimus - versus everolimus - eluting stents for unprotected left main coronary artery disease. J Am Coll Cardiol 2013. Epud ahead of print.</mixed-citation></ref><ref id="B29"><label>29.</label><mixed-citation>Daemen J, Wenaweser P, Tsuchida K et al. Early and late coronary stent thrombosis of sirolimus - eluting and paclitaxel - eluting stents in routine clinical practice: data from a large two - institutional cohort study. Lancet 2007; 369 (9562): 667-78.</mixed-citation></ref><ref id="B30"><label>30.</label><mixed-citation>Chieffo A, Park S.J, Meliga E et al. Late and very late stent thrombosis following drug - eluting stent implantation in unprotected left main coronary artery: a multicentre registry. Eur Heart J 2008; 29: 2108-15.</mixed-citation></ref><ref id="B31"><label>31.</label><mixed-citation>Sharma S.K, Baber U. The shifting pendulum for DAPT after PCI. Balancing long - term risks for bleeding and thrombosis. J Am Coll Cardiol 2015; 66 (9): 1046-9.</mixed-citation></ref></ref-list></back></article>
