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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">CardioSomatics</journal-id><journal-title-group><journal-title xml:lang="en">CardioSomatics</journal-title><trans-title-group xml:lang="ru"><trans-title>CardioСоматика</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2221-7185</issn><issn publication-format="electronic">2658-5707</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">45386</article-id><article-id pub-id-type="doi">10.26442/CS45386</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Lipotoxicity damage of myocardium in obesity</article-title><trans-title-group xml:lang="ru"><trans-title>Липотоксическое поражение миокарда при ожирении</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Gritsenko</surname><given-names>O. V</given-names></name><name xml:lang="ru"><surname>Гриценко</surname><given-names>Олеся Валерьевна</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук, врач-кардиолог, науч. сотр.</p></bio><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff7"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Chumakova</surname><given-names>G. A</given-names></name><name xml:lang="ru"><surname>Чумакова</surname><given-names>Галина Александровна</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, проф. каф. терапии и общей врачебной практики ФПК и ППС, вед. науч. сотр.</p></bio><email>g.a.chumakova@mail.ru</email><xref ref-type="aff" rid="aff7"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Elchaninova</surname><given-names>S. A</given-names></name><name xml:lang="ru"><surname>Ельчанинова</surname><given-names>Светлана Александровна</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р биол. наук, проф., зав каф. биохимии и клинической лабораторной диагностики</p></bio></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Veselovskaya</surname><given-names>N. G</given-names></name><name xml:lang="ru"><surname>Веселовская</surname><given-names>Надежда Григорьевна</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, зав. кардиологическим отд-нием №4, ст. науч. сотр.</p></bio><xref ref-type="aff" rid="aff8"/><xref ref-type="aff" rid="aff7"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Shevlyakov</surname><given-names>I. V</given-names></name><name xml:lang="ru"><surname>Шевляков</surname><given-names>Иван Валерьевич</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач</p></bio><email>preobrajensky89@mail.ru</email><xref ref-type="aff" rid="aff8"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kalugina</surname><given-names>O. A</given-names></name><name xml:lang="ru"><surname>Калугина</surname><given-names>Ольга Александровна</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач</p></bio><email>heartdoc@mail.ru</email><xref ref-type="aff" rid="aff8"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Altay Regional Cardiological Dispensary</institution></aff><aff><institution xml:lang="ru">КГБУЗ АККД, ФГБНУ НИИ КПССЗ</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Science Research Institute for Complex Issues of Cardiovascular Diseases</institution></aff><aff><institution xml:lang="ru">ФГБОУ ВО АГМУ, ФГБНУ НИИ КПССЗ</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">Science Research Institute for Complex Issues of Cardiovascular Diseases</institution></aff><aff><institution xml:lang="ru">ФГБОУ ВО АГМУ</institution></aff></aff-alternatives><aff-alternatives id="aff4"><aff><institution xml:lang="en">Altay State Medical University of the Ministry of Health of the Russian Federation</institution></aff><aff><institution xml:lang="ru">КГБУЗ АККД, ФГБНУ НИИ КПССЗ</institution></aff></aff-alternatives><aff-alternatives id="aff5"><aff><institution xml:lang="en">Altay State Medical University of the Ministry of Health of the Russian Federation</institution></aff><aff><institution xml:lang="ru">КГБУЗ АККД</institution></aff></aff-alternatives><aff-alternatives id="aff6"><aff><institution xml:lang="en">Altay Regional Cardiological Dispensary</institution></aff><aff><institution xml:lang="ru">КГБУЗ АККД</institution></aff></aff-alternatives><aff id="aff7"><institution>Science Research Institute for Complex Issues of Cardiovascular Diseases</institution></aff><aff id="aff8"><institution>Altay Regional Cardiological Dispensary</institution></aff><pub-date date-type="pub" iso-8601-date="2017-12-15" publication-format="electronic"><day>15</day><month>12</month><year>2017</year></pub-date><volume>8</volume><issue>4</issue><issue-title xml:lang="en">NO4 (2017)</issue-title><issue-title xml:lang="ru">ТОМ 8, №4 (2017)</issue-title><fpage>36</fpage><lpage>40</lpage><history><date date-type="received" iso-8601-date="2020-09-24"><day>24</day><month>09</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2017, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2017, ООО "Эко-Вектор"</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">ООО "Эко-Вектор"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://cardiosomatics.ru/2221-7185/article/view/45386">https://cardiosomatics.ru/2221-7185/article/view/45386</self-uri><abstract xml:lang="en"><p>In this article discusses the main mechanisms of development lipolitic damage of myocardial and morphological and structural changes of the heart in obesity.</p></abstract><trans-abstract xml:lang="ru"><p>В статье рассматриваются основные механизмы развития липотоксического поражения миокарда и особенности морфологических и структурных изменений сердца при ожирении</p></trans-abstract><kwd-group xml:lang="en"><kwd>lipotoxicity</kwd><kwd>lipotoxicity cardiomyopathy</kwd><kwd>obesity</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>липотоксичность</kwd><kwd>липотоксическая кардиомиопатия</kwd><kwd>ожирение</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Berrington de Gonzalez A, Hartge P, Cerhan J.R. et al. 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