CardioSomaticsCardioSomaticsCardioСоматика2221-71852658-5707Eco-Vector4593610.26442/2221-7185_2018.1.17-25ArticlesСтатьиReview ArticleClinical efficacy of pitavastatinКлиническая эффективность питавастатинаAronovD. MАроновДавид Меерович

д-р мед. наук, проф., заслуженный деятель науки РФ, рук. лаб.

BubnovaM. GБубноваМарина Геннадьевна

д-р мед. наук, проф., рук. отд

mbubnova@gnicPM.ruNational Medical Research Center of Preventive Medicine of the Ministry of Health of the Russian FederationФГБУ «НМИЦ профилактической медицины»1503201891VOL 9, NO1 (2018)ТОМ 9, №1 (2018)172525092020Copyright ©; 2018, Eco-VectorCopyright ©; 2018, ООО "Эко-Вектор"2018Eco-VectorООО "Эко-Вектор"https://creativecommons.org/licenses/by-nc-sa/4.0https://cardiosomatics.ru/2221-7185/article/view/45936

In the review article, anti-hyperlipidemic effects of a new synthetic statin, pitavastatin, are compared with similar effects of other statins. Attention is drawn to the ability of the drug to significantly increase the concentration of high-density lipoprotein cholesterol (by 19.3%!). A number of important, including previously unknown, pleiotropic effects of the drug are considered.

В обзорной статье рассматриваются антигиперлипидемические эффекты нового синтетического статина - питавастатина в сравнении с подобными эффектами других статинов. Обращается внимание на способность препарата значительно увеличивать концентрацию холестерина липопротеидов высокой плотности (на 19,3%!). Рассматривается ряд важных, в том числе ранее неизвестных плейотропных эффектов препарата.

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