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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">CardioSomatics</journal-id><journal-title-group><journal-title xml:lang="en">CardioSomatics</journal-title><trans-title-group xml:lang="ru"><trans-title>CardioСоматика</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2221-7185</issn><issn publication-format="electronic">2658-5707</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">686003</article-id><article-id pub-id-type="doi">10.17816/CS686003</article-id><article-id pub-id-type="edn">ZTMSLM</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Case reports</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Клинические случаи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">A case of recurrent pericarditis</article-title><trans-title-group xml:lang="ru"><trans-title>Клинический случай рецидивирующего перикардита</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0000-9183-4657</contrib-id><name-alternatives><name xml:lang="en"><surname>Vybach</surname><given-names>Maria V.</given-names></name><name xml:lang="ru"><surname>Выбач</surname><given-names>Мария Викторовна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>sansevera555@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8931-2435</contrib-id><name-alternatives><name xml:lang="en"><surname>Koryakova</surname><given-names>Nina V.</given-names></name><name xml:lang="ru"><surname>Корякова</surname><given-names>Нина Витальевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Medicine)</p></bio><bio xml:lang="ru"><p>канд. мед. наук</p></bio><email>tnk28@inbox.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8901-3363</contrib-id><contrib-id contrib-id-type="spin">3910-7360</contrib-id><name-alternatives><name xml:lang="en"><surname>Vezikova</surname><given-names>Natalia N.</given-names></name><name xml:lang="ru"><surname>Везикова</surname><given-names>Наталья Николаевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Medicine), Professor</p></bio><bio xml:lang="ru"><p>д-р мед. наук, профессор</p></bio><email>vezikov23@mail.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3353-3220</contrib-id><contrib-id contrib-id-type="spin">8999-9238</contrib-id><name-alternatives><name xml:lang="en"><surname>Ryabkov</surname><given-names>Vadim A.</given-names></name><name xml:lang="ru"><surname>Рябков</surname><given-names>Вадим Александрович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Medicine)</p></bio><bio xml:lang="ru"><p>канд. мед. наук</p></bio><email>vad-ryabkov@yandex.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4122-5551</contrib-id><name-alternatives><name xml:lang="en"><surname>Polskaya</surname><given-names>Irina I.</given-names></name><name xml:lang="ru"><surname>Польская</surname><given-names>Ирина Игоревна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Medicine)</p></bio><bio xml:lang="ru"><p>канд. мед. наук</p></bio><email>irina_polskaya82@mail.ru</email><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Republican Hospital named after V.A. Baranov</institution></aff><aff><institution xml:lang="ru">Республиканская больница имени В.А. Баранова</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Petrozavodsk State University</institution></aff><aff><institution xml:lang="ru">Петрозаводский государственный университет</institution></aff></aff-alternatives><pub-date date-type="preprint" iso-8601-date="2026-08-19" publication-format="electronic"><day>19</day><month>08</month><year>2026</year></pub-date><pub-date date-type="pub" iso-8601-date="2026-09-06" publication-format="electronic"><day>06</day><month>09</month><year>2026</year></pub-date><volume>17</volume><issue>1</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>61</fpage><lpage>69</lpage><history><date date-type="received" iso-8601-date="2025-06-27"><day>27</day><month>06</month><year>2025</year></date><date date-type="accepted" iso-8601-date="2026-03-04"><day>04</day><month>03</month><year>2026</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2026, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2026, ООО "Эко-Вектор"</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">ООО "Эко-Вектор"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/" start_date="2029-09-06"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-nd/4.0/</ali:license_ref></license></permissions><self-uri xlink:href="https://cardiosomatics.ru/2221-7185/article/view/686003">https://cardiosomatics.ru/2221-7185/article/view/686003</self-uri><abstract xml:lang="en"><p><bold>BACKGROUND:</bold><bold><italic> </italic></bold>Recurrent pericarditis requires a comprehensive evaluation to rule out infectious, autoimmune, and oncological conditions. Idiopathic recurrent pericarditis is considered an autoinflammatory disease and is not characterized by specific immunological disorders, particularly autoantibody production. Given the rarity of true idiopathic pericarditis, a thorough search for an underlying cause is essential, especially when markers suggestive of autoimmune or malignant disease are present.</p> <p><bold>CASE DESCRIPTION:</bold><bold><italic> </italic></bold>We present a case of recurrent pericarditis in an elderly male patient. The case is notable for repeated detection of immunological markers typical of systemic connective tissue diseases, along with recurrent lymphadenopathy. Despite ongoing follow-up, no specific underlying etiology could be identified, and the diagnosis was established as idiopathic recurrent pericarditis. With continuous colchicine therapy at 1 mg/day for 6 months, no further pericarditis recurrences occurred. The patient tolerates the treatment well, and no adverse effects have been reported. Follow-up is ongoing.</p> <p><bold>CONCLUSION:</bold><bold><italic> </italic></bold>This case highlights the diagnostic challenges of recurrent pericarditis and underscores the need for a multidisciplinary approach involving cardiologists, rheumatologists, oncologists, and other specialists.</p></abstract><trans-abstract xml:lang="ru"><p><bold>Обоснование.</bold><bold> </bold>Рецидивирующий перикардит требует проведения комплексного обследования пациента для исключения инфекционных, аутоиммунных и онкологических заболеваний. Идиопатический рецидивирующий перикардит относится к аутовоспалительным заболеваниям, для которых не характерны специфические иммунологические нарушения, в частности продукция аутоантител. Учитывая редкость истинного идиопатического перикардита, необходим тщательный этиологический поиск, особенно при наличии маркёров аутоиммунных или онкологических заболеваний.</p> <p><bold>Описание случая.</bold><bold> </bold>В статье представлен клинический случай рецидивирующего перикардита у мужчины пожилого возраста. Особенностью наблюдения является неоднократное выявление иммунологических маркёров, характерных для системных заболеваний соединительной ткани, в сочетании с рецидивирующей лимфаденопатией. Несмотря на динамическое наблюдение, специфическую этиологию заболевания установить не удалось. Диагноз был сформулирован как идиопатический рецидивирующий перикардит. На фоне постоянной терапии колхицином в дозе 1 мг/сут в течение 6 месяцев рецидивов перикардита не отмечено. Пациент хорошо переносит лечение, побочных эффектов не зарегистрировано. Продолжается динамическое наблюдение.</p> <p><bold>Заключение.</bold><bold> </bold>Данный клинический случай демонстрирует трудности дифференциальной диагностики рецидивирующего перикардита и подчёркивает необходимость мультидисциплинарного подхода с участием кардиологов, ревматологов, онкологов и других специалистов.</p></trans-abstract><kwd-group xml:lang="en"><kwd>recurrent pericarditis</kwd><kwd>autoinflammatory diseases</kwd><kwd>autoimmune diseases</kwd><kwd>immunological markers</kwd><kwd>lymphadenopathy</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>рецидивирующий перикардит</kwd><kwd>аутовоспалительные заболевания</kwd><kwd>аутоиммунные заболевания</kwd><kwd>иммунологические маркёры</kwd><kwd>лимфаденопатия</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Arutyunov GP, Paleev FN, Tarlovskaya EI, et al. Pericarditis. Clinical Guidelines 2022. 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