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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">CardioSomatics</journal-id><journal-title-group><journal-title xml:lang="en">CardioSomatics</journal-title><trans-title-group xml:lang="ru"><trans-title>CardioСоматика</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2221-7185</issn><issn publication-format="electronic">2658-5707</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">697662</article-id><article-id pub-id-type="doi">10.17816/CS697662</article-id><article-id pub-id-type="edn">OVIDAZ</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Original study articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Оригинальные статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Clinical and epidemiological aspects of atrial fibrillation and/or atrial flutter in patients with diabetes mellitus: a cross-sectional retrospective population-based study</article-title><trans-title-group xml:lang="ru"><trans-title>Клинико-эпидемиологические аспекты фибрилляции и/или трепетания предсердий у больных с сахарным диабетом: одномоментное ретроспективное популяционное исследование</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0000-9333-2757</contrib-id><contrib-id contrib-id-type="spin">9299-6280</contrib-id><name-alternatives><name xml:lang="en"><surname>Myasnikova</surname><given-names>Anastasia S.</given-names></name><name xml:lang="ru"><surname>Мясникова</surname><given-names>Анастасия Сергеевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>asymyasnikova@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5178-6029</contrib-id><contrib-id contrib-id-type="spin">4524-4803</contrib-id><name-alternatives><name xml:lang="en"><surname>Bondarenko</surname><given-names>Irina Z.</given-names></name><name xml:lang="ru"><surname>Бондаренко</surname><given-names>Ирина Зиятовна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Medicine)</p></bio><bio xml:lang="ru"><p>д-р мед. наук</p></bio><email>bondarenko.irina@endocrincentr.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1831-8052</contrib-id><contrib-id contrib-id-type="spin">3778-0968</contrib-id><name-alternatives><name xml:lang="en"><surname>Shatskaya</surname><given-names>Olga A.</given-names></name><name xml:lang="ru"><surname>Шацкая</surname><given-names>Ольга Александровна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Medicine)</p></bio><bio xml:lang="ru"><p>канд. мед. наук</p></bio><email>shackaya.olga@endocrincentr.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9247-4523</contrib-id><contrib-id contrib-id-type="spin">6338-4990</contrib-id><name-alternatives><name xml:lang="en"><surname>Khamnagadaev</surname><given-names>Igor A.</given-names></name><name xml:lang="ru"><surname>Хамнагадаев</surname><given-names>Игорь Алексеевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Medicine)</p></bio><bio xml:lang="ru"><p>д-р мед. наук</p></bio><email>hamnagadaev.Igor@endocrincentr.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4917-1743</contrib-id><contrib-id contrib-id-type="spin">6468-2750</contrib-id><name-alternatives><name xml:lang="en"><surname>Belousov</surname><given-names>Leonid A.</given-names></name><name xml:lang="ru"><surname>Белоусов</surname><given-names>Леонид Александрович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>belousov.leonid@endocrincentr.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7328-6316</contrib-id><contrib-id contrib-id-type="spin">5307-9820</contrib-id><name-alternatives><name xml:lang="en"><surname>Melkozerov</surname><given-names>Konstantin V.</given-names></name><name xml:lang="ru"><surname>Мелкозёров</surname><given-names>Константин Викторович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Medicine)</p></bio><bio xml:lang="ru"><p>канд. мед. наук</p></bio><email>melkozerov.k@endocrincentr.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6267-3724</contrib-id><contrib-id contrib-id-type="spin">1275-2773</contrib-id><name-alternatives><name xml:lang="en"><surname>Bulavina</surname><given-names>Irina A.</given-names></name><name xml:lang="ru"><surname>Булавина</surname><given-names>Ирина Андреевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>bulavina.irina@endocrincwntr.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3366-368X</contrib-id><contrib-id contrib-id-type="spin">7650-3845</contrib-id><name-alternatives><name xml:lang="en"><surname>Tiurin</surname><given-names>Nikolai I.</given-names></name><name xml:lang="ru"><surname>Тюрин</surname><given-names>Николай Игоревич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>tyurin.nikolay@endocrincentr.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1387-683X</contrib-id><contrib-id contrib-id-type="spin">9349-6790</contrib-id><name-alternatives><name xml:lang="en"><surname>Bukatsello</surname><given-names>Raisa S.</given-names></name><name xml:lang="ru"><surname>Букацелло</surname><given-names>Раиса Станиславовна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>bukatsello.raisa@endocrincentr.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6318-1345</contrib-id><contrib-id contrib-id-type="spin">7707-6891</contrib-id><name-alternatives><name xml:lang="en"><surname>Gomova</surname><given-names>Irina S.</given-names></name><name xml:lang="ru"><surname>Гомова</surname><given-names>Ирина Сергеевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Medicine)</p></bio><bio xml:lang="ru"><p>канд. мед. наук</p></bio><email>gomova.irina@endocrincentr.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5573-0754</contrib-id><contrib-id contrib-id-type="spin">5342-7253</contrib-id><name-alternatives><name xml:lang="en"><surname>Kalashnikov</surname><given-names>Victor Yu.</given-names></name><name xml:lang="ru"><surname>Калашников</surname><given-names>Виктор Юрьевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Medicine), Professor</p></bio><bio xml:lang="ru"><p>д-р мед. наук, профессор</p></bio><email>kalashnikov.victor@endocrincentr.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5057-127X</contrib-id><contrib-id contrib-id-type="spin">7584-7015</contrib-id><name-alternatives><name xml:lang="en"><surname>Shestakova</surname><given-names>Marina V.</given-names></name><name xml:lang="ru"><surname>Шестакова</surname><given-names>Марина Владимировна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Medicine), Professor, Academician of the Russian Academy of Sciences</p></bio><bio xml:lang="ru"><p>д-р мед. наук, профессор, академик РАН</p></bio><email>shestakova.marina@endocrincentr.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Endocrinology Research Centre</institution></aff><aff><institution xml:lang="ru">Национальный медицинский исследовательский центр эндокринологии имени академика И.И. Дедова</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Russian National Research Medical University named after N.I. Pirogov</institution></aff><aff><institution xml:lang="ru">Российский национальный исследовательский медицинский университет имени Н.И. Пирогова</institution></aff></aff-alternatives><pub-date date-type="preprint" iso-8601-date="2025-12-26" publication-format="electronic"><day>26</day><month>12</month><year>2025</year></pub-date><pub-date date-type="pub" iso-8601-date="2026-02-13" publication-format="electronic"><day>13</day><month>02</month><year>2026</year></pub-date><volume>16</volume><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>308</fpage><lpage>322</lpage><history><date date-type="received" iso-8601-date="2025-12-04"><day>04</day><month>12</month><year>2025</year></date><date date-type="accepted" iso-8601-date="2025-12-26"><day>26</day><month>12</month><year>2025</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2025, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2025, ООО "Эко-Вектор"</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">ООО "Эко-Вектор"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/" start_date="2029-02-13"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-nd/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://cardiosomatics.ru/2221-7185/article/view/697662">https://cardiosomatics.ru/2221-7185/article/view/697662</self-uri><abstract xml:lang="en"><p><bold>BACKGROUND: </bold>Diabetes mellitus (DM), atrial fibrillation (AF), and atrial flutter (AFL) are among the most prevalent cardiovascular disorders, with their incidence steadily increasing worldwide. The coexistence of DM with AF or AFL is associated with a more severe disease course and a less favorable prognosis compared with each condition occurring independently.</p> <p><bold>AIM: </bold>To analyze current clinical and epidemiological aspects of atrial fibrillation (AF) and atrial flutter (AFL) in patients with diabetes mellitus, including sex- and age-related characteristics, distribution by subtype, and the relationship between diabetes mellitus and outcomes after radiofrequency catheter ablation.</p> <p><bold>METHODS: </bold>A retrospective analysis of medical records was performed for patients hospitalized in the cardiology department of the National Medical Research Center for Endocrinology named after Academician I.I. Dedov (Moscow, Russia) between January 1, 2017, and October 30, 2025.</p> <p><bold>RESULTS: </bold>Among the analyzed discharge summaries, 218 patients (24.9%) had type 2 diabetes mellitus. Of these patients, 30.7% had paroxysmal AF, 22.5% persistent AF, 15.1% persistent AF combined with AFL, 12.8% persistent AFL, 12.4% paroxysmal AF combined with AFL, and 6.5% paroxysmal AFL. Comparative analysis of patient groups with and without diabetes mellitus did not demonstrate convincing evidence of an effect of impaired carbohydrate metabolism on the outcomes of radiofrequency catheter ablation.</p> <p><bold>CONCLUSION: </bold>This study clearly demonstrates the prevalence of diabetes mellitus among patients with AF and AFL and identifies criteria for further investigation of the impact of diabetes mellitus on the outcomes and progression of AF. Further study of this issue is required.</p></abstract><trans-abstract xml:lang="ru"><p><bold>Обоснование. </bold>Сахарный диабет, фибрилляция предсердий (ФП) и трепетание предсердий (ТП) относятся к числу широко распространённых кардиологических заболеваний, при этом следует отметить, что частота данных патологий в настоящее время неуклонно растёт. При сочетанном течении сахарного диабета с ФП или ТП заболевание протекает тяжелее, а прогноз представляется менее благоприятным в сравнении с ситуациями, когда эти патологии присутствуют обособленно друг от друга.</p> <p><bold>Цель </bold>— проанализировать актуальные клинико-эпидемиологические аспекты ФП и ТП у больных с сахарным диабетом: оценить характеристику групп по полу и возрасту, распределить их по нозологическим формам, выявить закономерность между положительным эффектом после проведённой радиочастотной абляции и наличием сахарного диабета у пациентов.</p> <p><bold>Методы. </bold>Проведён ретроспективный анализ историй болезни пациентов, находившихся на стационарном лечении в кардиологическом отделении Национального медицинского исследовательского центра эндокринологии имени академика И.И. Дедова (Москва, Россия) в период с 01.01.2017 по 30.10.2025.</p> <p><bold>Результаты. </bold>Среди проанализированных выписных эпикризов пациентов выявлено 218 (24,9%) пациентов с сахарным диабетом 2-го типа. Из них у 30,7% — пароксизмальная форма ФП, у 22,5% — персистирующая форма ФП, у 15,1% — персистирующая форма ФП и ТП, у 12,8% — персистирующая форма ТП, у 12,4% — пароксизмальная форма ФП и ТП, у 6,5% — пароксизмальная форма ТП. В ходе анализа групп пациентов с сахарным диабетом и без него не получено убедительных данных о влиянии данного нарушения углеводного обмена на исход проводимой радиочастотной абляции.</p> <p><bold>Заключение. </bold>Данное исследование позволило наглядно продемонстрировать распространённость сахарного диабета среди пациентов с ФП и ТП, а также выявить критерии дальнейшего изучения влияния сахарного диабета на исход и прогрессирование ФП. Требуется дальнейшее изучение данного вопроса.</p></trans-abstract><kwd-group xml:lang="en"><kwd>epidemiology</kwd><kwd>atrial fibrillation</kwd><kwd>diabetes mellitus</kwd><kwd>sodium-glucose cotransporter 2</kwd><kwd>glucagon-like peptide-1</kwd><kwd>radiofrequency catheter ablation</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>эпидемиология</kwd><kwd>фибрилляция предсердий</kwd><kwd>сахарный диабет</kwd><kwd>натрий-глюкозный котранспортёр 2-го типа</kwd><kwd>глюкагоноподобный пептид-1</kwd><kwd>радиочастотная абляция</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Dedov II, Shestakova MV, Sukhareva OYu, editors. Standards of specialized diabetes care. 12th edition. Moscow; 2025.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Gherasim L. Association of Atrial Fibrillation with Diabetes Mellitus, High Risk Comorbidities. 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