Influence of alginate-fabric coating with silver nanoparticles on the course of wound process in laboratory animals

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Alginates with various modifying additives (for example, chitosan) and various methods of physical treatment are used in the design of prototypes of innovative wound dressing. The aim of this study was to create and explore the properties of a prototype of textile-based sodium alginate wound dressing containing silver nanoparticles subjected to10 freeze cycles, and to evaluate its efficacy on the course of the purulent wound process in rats. The study showed that the developed technology of 10-fold cyclic freezing makes it possible to significantly increase the amount of silver nanoparticles in the composition of textile-based sodium alginate wound dressing, primarily due to silver nanoparticles that have a diameter not larger than 15 nm, and are characterized by the highest antibacterial activity. The use of the developed wound dressing with silver nanoparticles reduces metabolic disturbances when the nonspecific defense system response occurs in the wound tissue; on the 3rd and 5th day after wounding less pronounced changes in free radical oxidation indices were found, the levels of antioxidant defence enzymes (catalase and superoxide dismutase) in wound tissue were lower than those observed after the use of wound dressing with silver nanoparticles, but not containing alginate, or after wound debridement without alginate or nanoparticles done every day.

Sobre autores

V. Malyshko

Kuban State Medical University, Ministry of Health of the Russian Federation;Federal Research Center "Southern Scientific Center of the Russian Academy of Sciences”

Krasnodar, Russia;Rostov-on-Don, Russia

L. Fedulova

V.M. Gorbatov Federal Scientific Center for Food Systems

Moscow, Russia

M. Sokolov

Kuban State University

Krasnodar, Russia

A. Moiseev

Kuban State Agrarian University

Krasnodar, Russia

A. Basov

Kuban State Medical University, Ministry of Health of the Russian Federation;Kuban State University

Krasnodar, Russia;Krasnodar, Russia

A. Dorohova

Federal Research Center "Southern Scientific Center of the Russian Academy of Sciences”;Kuban State University

Email: 013194@mail.ru
Rostov-on-Don, Russia;Krasnodar, Russia

D. Shashkov

Kuban State University

Krasnodar, Russia

S. Dzhimak

Federal Research Center "Southern Scientific Center of the Russian Academy of Sciences”;Kuban State University

Rostov-on-Don, Russia;Krasnodar, Russia

Bibliografia

  1. H. A. Albarqi, A. A. Alqahtani, I. Ullah, et al., AAPS Pharm. Sci. Tech., 23 (2), 72 (2022).
  2. L. Wei, J. Tan, L. Li, et al., Int. J. Mol. Sci., 23 (3), 1249 (2022).
  3. R. E. Abouzeid, A. Salama, and E. M. El-Fakharany, Molecules, 27, 697 (2022).
  4. X. Huang, H. Jing, X. Du, et al., Int. J. Biol. Macromol., 200, 1 (2022).
  5. Y. Wang, L. Su, Y. Hou, et al., Macromol. Biosci., 22 (4), e2100352 (2022).
  6. N. Shojarazavi, S. Mashayekhan, H. Pazooki, et al., J. Biomater. Appl., 36 (5), 803 (2021).
  7. E. Kim, J. M. Seok, S. B. Bae, et al., Biomacromolecules, 22 (5), 1921 (2021).
  8. C. C. Chen, Y. Y. Chen, C. C. Yeh, et al., Front. Pharmacol., 12, 746496 (2021).
  9. A. Basov, L. Fedulova, E. Vasilevskaya, et al., Saudi J. Biol. Sci., 28 (3), 1826 (2021).
  10. S. Tian, Y. Hu, X. Chen, et al., Int. J. Biol. Macromol., 195, 515 (2022).
  11. H. Murugaiah, C. L. Teh, K. C. Loh, et al., Molecules, 26 (21), 6414 (2021).
  12. S. S. Dzhimak, V. V. Malyshko, A. I. Goryachko, et al., Rus. Phys. J., 62 (2), 314 (2019).
  13. S. S. Dzhimak, V. V. Malyshko, A. I. Goryachko, et al., Nanotech.Rus., 14, 48 (2019).
  14. G. F. Kopytov, V. V. Malyshko, A. A. Elkina, et al., Rus. Phys. J., 63 (6), 989 (2020).
  15. A. Basov, S. Dzhimak, M. Sokolov, et al., Nanomaterials, 12, 1164 (2022).
  16. S. S. Dzhimak, M. E. Sokolov, A. A. Basov, et al., Nanotech.Rus., 11, 835 (2016).
  17. А. А. Басов, В. В. Малышко, С. Р. Федосов и др., Патент РФ № 150504, № 5 (2015).
  18. В. В. Малышко, С. С. Джимак, Л. В. Ломакина и др., Патент РФ № 2770277, № 11 (2022).
  19. I. Petriev, P. Pushankina, M. Baryshev, and N. Shostak, Int. J. Mol. Sci., 23 (1), 228 (2022).
  20. I. S. Petriev, P. D. Pushankina, I. S. Lutsenko, and M. G. Baryshev, Tech. Phys. Let., 47, 803 (2021).
  21. А. А. Басов, И. М. Быков, С. Р. Федосов, В. В. Малышко, Патент РФ № 2455703, № 19 (2012).
  22. М. О. Гомзикова, А. Г. Маланьева и З. Ю. Сираева, Основы проведения биомедицинских исследований на лабораторных животных: учеб. пособие (МеДДоК, Казань, 2021).
  23. A. Я. Яшин, Рос. хим. журн., № 2, 130 (2008).
  24. J. F. Robyt, R. J. Ackerman, and C. G. Chittenden, Arch. Biochem. Biophys., 147, 262 (1971).
  25. R. Beers and I. Sizer, J. Biol. Chem., 195, 133 (1952).
  26. A. A. Basov, S. V. Kozin, I. M. Bikov, et al. Biol. Bull., 46 (6), 531 (2019).
  27. B. A. Костюк, A. И. Потапович и Ж. И. Ковалева, Вопр. мед. хим. 2, 88 (1990).
  28. A. Kravtsov, S. Kozin, A. Basov, et al. Molecules 27 (1), 243 (2022).
  29. А. А. Басов, И. И. Павлюченко, А. М. Плаксин и С. Р. Федосов, Вестн. новых мед. технол. 4, 67 (2003).
  30. И. И. Павлюченко, А. А. Басов и С. Р. Федосов, Патент РФ № 54787, № 21 (2007).
  31. И. И. Павлюченко, C. P. Федосов и A. A. Басов, Патент РФ № 2006611562 (2006).
  32. I. M. Bykov, A. A. Basov, V. V. Malyshko, et al., Bull. Exp. Biol. and Med., 163 (2), 268 (2017).
  33. G. Tao, Y. Wang, R. Cai, et al., Mater. Sci. Eng. C, 101, 341 (2019).
  34. H. He, G. Tao, Y. Wang, et al., Mater. Sci. Eng. C, 80, 509 (2017).
  35. H. Muhammad Tahir, F. Saleem, S. Ali, et al., J. Basic. Microbiol., 60 (5), 458 (2020).
  36. S. Roy and T. K. Das, J. Appl. Spectrosc., 82, 598 (2015).
  37. Z. Tan, X. Guo, Y. Yin, et al. Environ. Sci. Technol., 53 (23), 13802 (2019).
  38. S. J. Yu, Y. G. Yin, J. B. Chao, et al., Environ. Sci. Technol., 48 (1), 403 (2014).
  39. G. Xiaoru, Y. Yongguang, T. Zhiqiang, et al., Environ. Sci. Technol., 52 (12), 6928 (2018).
  40. С. Р. Туйсин и И. В. Богданов, Фундаментал. исслед. 4, 81 (2010).
  41. A. A. Basov, S. R. Fedosov, V. V. Malyshko, et al., J. Wound Care, 30 (4), 312 (2021).
  42. I. Y. Tsymbalyuk, A. M. Manuilov, K. A. Popov, and A. A. Basov, Novosti Khirurgii, 25 (5), 447 (2017).
  43. R. Vazquez-Munoz, B. Borrego, K. Juarez-Moreno, et al., Toxicol. Lett., 276, 11 (2017).
  44. Т. И. Лебедева, И. А. Красочко и П. А. Красочко, Вестник АПК Верхневолжья, 2 (54), 73 (2021).

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