Солнечный витамин D3 – многоликий, загадочный, необходимый

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Аннотация

Рассматривается значение витамина D3 для поддержания уровня здоровья в условиях острой респираторной и сосудистой патологии COVID-19. Физиологический дефицит витамина документируется как негативный прогноз подверженности влиянию вируса и тяжести заболевания. Многие клинические и экспериментальные исследования свидетельствуют, что витамин D3 выполняет функцию контроля гемоваскулярного гомеостаза – эндотелия сосудистой стенки, иммунологических реакций, свертывания и реологических свойств крови, системной гемодинамики и др. Многообразие эффектов определяется транскрипционной ролью рецептора витамина D3, экспрессирующего генные мишени синтеза функциональных белков. Рассматриваются возможности суплементации, поддержания уровня витамина D3 и его химических метаболитов, для профилактической и лечебной стратегии COVID-19.

Об авторах

О. А. Гомазков

Научно-исследовательский институт биомедицинской химии им. В.Н. Ореховича

Автор, ответственный за переписку.
Email: oleg-gomazkov@yandex.ru
Россия, Москва

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