Effect of copper(II) ions on physicochemical properties of lecithin liposomes in aqueous medium
- Autores: Beletskaya P.D.1, Dubovik A.S.1, Shvydkiy V.O.1, Shishkina L.N.1
- 
							Afiliações: 
							- N. M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences
 
- Edição: Volume 99, Nº 6 (2025)
- Páginas: 964-970
- Seção: БИОФИЗИЧЕСКАЯ ХИМИЯ И ФИЗИКО-ХИМИЧЕСКАЯ БИОЛОГИЯ
- ##submission.dateSubmitted##: 26.09.2025
- ##submission.datePublished##: 15.06.2025
- URL: https://cardiosomatics.ru/0044-4537/article/view/691394
- DOI: https://doi.org/10.31857/S0044453725060167
- EDN: https://elibrary.ru/hhzcdh
- ID: 691394
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		                                					Resumo
The interaction of copper(II) ions with natural lipids (soybean lecithin with different phospholipid composition) in aqueous medium has been studied. Using methods of thin-layer chromatography, dynamic light scattering and mathematical processing of UV-spectra by Gauss method, it was revealed that in aqueous medium lecithin forms rather large liposomes with a diameter of about 900 nm, the size of which decreases in the presence of copper(II) ions regardless of their concentration. It was found that copper(II) ions both initiate lipid peroxidation processes and form complexes with polar «heads» of phospholipids. It is shown that these processes depend on the composition of lecithin lipids and their ability to oxidation.
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Sobre autores
P. Beletskaya
N. M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences
														Email: belet-polina@yandex.ru
				                					                																			                												                								Moscow, Russia						
A. Dubovik
N. M. Emanuel Institute of Biochemical Physics, Russian Academy of SciencesMoscow, Russia
V. Shvydkiy
N. M. Emanuel Institute of Biochemical Physics, Russian Academy of SciencesMoscow, Russia
L. Shishkina
N. M. Emanuel Institute of Biochemical Physics, Russian Academy of SciencesMoscow, Russia
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