Small Non-Coding RNAs of Bacteria are Global Regulators of the Bacterial Life Cycle
- 作者: Skvortsova Y.V1, Grigorov A.S1, Bychenko O.S1, Azhikina T.L1
-
隶属关系:
- Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, RAS
- 期: 卷 51, 编号 5 (2025)
- 页面: 769-784
- 栏目: ОБЗОРНЫЕ СТАТЬИ
- URL: https://cardiosomatics.ru/0132-3423/article/view/695706
- DOI: https://doi.org/10.31857/S0132342325050045
- ID: 695706
如何引用文章
详细
Bacteria utilize a wide range of regulatory systems to adapt to life in various environmental conditions. Among these regulators, small non-coding RNAs (ncRNAs) play a particularly important role. Acting primarily at the post-transcriptional level, small ncRNAs enable bacteria to rapidly adjust expression of genes in response to external stimuli. They participate in the regulation of virtually all cellular processes, including replication, transcription, translation, energy and general metabolism, antibiotic resistance, bacterial virulence, as well as mechanisms associated with bacterial pathogenesis. Bacterial small ncRNAs are capable of mediating interactions between the bacterium and the host organism, directly modulating the expression of eukaryotic genes (most often those related to the immune response). Thus, ncRNAs serve as universal and powerful regulatory elements that ensure the survival and active functioning of bacteria under any adverse conditions.
作者简介
Y. Skvortsova
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, RAS
Email: ju.skvortsova@gmail.com
Moscow, Russia
A. Grigorov
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, RASMoscow, Russia
O. Bychenko
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, RASMoscow, Russia
T. Azhikina
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, RASMoscow, Russia
参考
- Eichner H., Karlsson J., Loh E. // Trends Microbiol. 2022. V. 30. P. 959–972. https://doi.org/10.1016/j.tim.2022.03.007
- Marek M.S., Johnson-Buck A., Walter N.G. // Phys. Chem. Chem. Phys. 2011. V. 13. P. 11524–11537. https://doi.org/10.1039/C1CP20576E
- Карпов А.С., Елкина Д.А., Орецкая Т.С., Кубарева Е.А. // Биоорг. химия. 2023. V. 49. P. 555–574. https://doi.org/10.31857/S0132342323060088
- Saberi F., Kamali M., Najafi A., Yazdanparast A., Moghaddam M.M. // Cell. Mol. Biol. Lett. 2016. V. 21. P. 1–17. https://doi.org/10.1186/s11658-016-0007-z
- Kawano M., Aravind Á., Storz G. // Mol. Microbiol. 2007. V. 64. P. 738–754. https://doi.org/10.1111/j.1365-2958.2007.05688.x
- Quendera A.P., Seixas A.F., Dos Santos R.F., Santos I., Silva J.P., Arraiano C.M., Andrade J.M. // Front. Mol. Biosci. 2020. V. 7. P. 78. https://doi.org/10.3389/fmolb.2020.00078
- Watkins D., Arya D.P. // Non-coding RNA Investig. 2019. V. 3. P. 28. https://doi.org/10.21037/ncri.2019.10.02
- Morfeldt E., Taylor D., von Gabain A., Arvidson S. // EMBO J. 1995. V. 14. P. 4569. https://doi.org/10.1002/j.1460-2075.1995.tb00136.x
- Novick R.P., Ross H., Projan S., Kornblum J., Kreiswirth B., Moghazeh S. // EMBO J. 1993. V. 12. P. 3967. https://doi.org/10.1002/j.1460-2075.1993.tb06074.x
- Chevalier C., Boisset S., Romilly C., Masquida B., Fechter P., Geissmann T., Vandenesch F., Romby P. // PLoS Pathog. 2010. V. 6. P. e1000809. https://doi.org/10.1371/journal.ppat.1000809
- Huntzinger E., Boisset S., Saveanu C., Benito Y., Geissmann T., Namane A., Lina G., Etienne J., Ehresmann B., Ehresmann C. // EMBO J. 2005. V. 24. P. 824–835. https://doi.org/10.1038/sj.emboj.7600572
- Papenfort K., Sun Y., Miyakoshi M., Vanderpool C.K., Vogel J. // Cell. 2013. V. 153. P. 426–437. https://doi.org/10.1016/j.cell.2013.03.003
- Kawamoto H., Koide Y., Morita T., Aiba H. // Mol. Microbiol. 2006. V. 61. P. 1013–1022. https://doi.org/10.1111/j.1365-2958.2006.05288.x
- Vanderpool C.K., Gottesman S. // Mol. Microbiol. 2004. V. 54. P. 1076–1089. https://doi.org/10.1111/j.1365-2958.2004.04348.x
- Wadler C.S., Vanderpool C.K. // Proc. Natl. Acad. Sci. USA. 2007. V. 104. P. 20454–20459. https://doi.org/10.1073/pnas.0708102104
- Giangrossi M., Prosseda G., Tran C.N., Brandi A., Colonna B., Falconi M. // Nucleic Acids Res. 2010. V. 38. P. 3362–3375. https://doi.org/10.1093/nar/gkq025
- Udekwu K.I., Darfeuille F., Vogel J., Reimegård J., Holmqvist E., Wagner E.G.H. // Genes Dev. 2005. V. 19. P. 2355–2366. https://doi.org/10.1101/gad.354405
- Leiva L.E., Katz A. // Microorganisms. 2022. V. 10. P. 723. https://doi.org/10.3390/microorganisms10040723
- Sharma C.M., Darfeuille F., Plantinga T.H., Vogel J. // Genes Dev. 2007. V. 21. P. 2804–2817. https://doi.org/10.1101/gad.447207
- Pfeiffer V., Papenfort K., Lucchini S., Hinton J.C., Vogel J. // Nat. Struct. Mol. Biol. 2009. V. 16. P. 840– 846. https://doi.org/10.1038/nsmb.1631
- Bandyra K.J., Said N., Pfeiffer V., Górna M.W., Vogel J., Luisi B.F. // Mol. Cell. 2012. V. 47. P. 943– 953. https://doi.org/10.1016/j.molcel.2012.07.015
- Večerek B., Moll I., Bläsi U. // EMBO J. 2007. V. 26. P. 965–975. https://doi.org/10.1038/sj.emboj.7601553
- Sonnleitner E., Gonzalez N., Sorger-Domenigg T., Heeb S., Richter A.S., Backofen R., Williams P., Hüttenhofer A., Haas D., Bläsi U. // Mol. Microbiol. 2011. V. 80. P. 868–885. https://doi.org/10.1111/j.1365-2958.2011.07620.x
- Prévost K., Desnoyers G., Jacques J.-F., Lavoie F., Massé E. // Genes Dev. 2011. V. 25. P. 385– 396. https://doi.org/10.1101/gad.2001711
- Brownlee G. // Nature New Biol. 1971. V. 229. P. 147– 149. https://doi.org/10.1038/newbio229147a0
- Burenina O.Y., Elkina D.A., Hartmann R.K., Oretskaya T.S., Kubareva E.A. // Biochemistry (Moscow). 2015. V. 80. P. 1429–1446. https://doi.org/10.1134/S0006297915110048
- Wassarman K.M., Storz G. // Cell. 2000. V. 101. P. 613–623. https://doi.org/10.1016/S0092-8674(00)80873-9
- Liu M.Y., Gui G., Wei B., Preston J.F., Oakford L., Yuksel U., Giedroc D.P., Romeo T. // J. Biol. Chem. 1997. V. 272. P. 17502–17510. https://doi.org/10.1074/jbc.272.28.17502
- Baker C.S., Morozov I., Suzuki K., Romeo T., Babitzke P. // Mol. Microbiol. 2002. V. 44. P. 1599–1610. https://doi.org/10.1046/j.1365-2958.2002.02982.x
- Lalaouna D., Eyraud A., Devinck A., Prévost K., Massé E. // Mol. Microbiol. 2019. V. 111. P. 473–486. https://doi.org/10.1111/mmi.14168
- Miyakoshi M., Chao Y., Vogel J. // EMBO J. 2015. V. 34. P. 1478–1492.
- Pagliuso A., Tham T.N., Allemand E., Robertin S., Dupuy B., Bertrand Q., Becavin C., Koutero M., Najburg V., Nahori M.A., Tangy F., Stavru F., Bessonov S., Dessen A., Muchardt C., Lebreton A., Komarova A.V., Cossart P. // Cell Host Microbe. 2019. V. 26. P. 823–835.e11. https://doi.org/10.1016/j.chom.2019.10.004
- Abdullah Z., Schlee M., Roth S., Mraheil M.A., Barchet W., Bottcher J., Hain T., Geiger S., Hayakawa Y., Fritz J.H., Civril F., Hopfner K.P., Kurts C., Ruland J., Hartmann G., Chakraborty T., Knolle P.A. // EMBO J. 2012. V. 31. P. 4153–4164. https://doi.org/10.1038/emboj.2012.274
- Cheng Y., Schorey J.S. // J. Exp. Med. 2018. V. 215. P. 2919–2935. https://doi.org/10.1084/jem.20180508
- Bychenko O.S., Khrulev A.A., Svetlova J.I., Tsvetkov V.B., Kamzeeva P.N., Skvortsova Y.V., Tupertsev B.S., Ivanov I.A., Aseev L.V., Khodarovich Y.M., Belyaev E.S., Kozlovskaya L.I., Zatsepin T.S., Azhikina T.L., Varizhuk A.M., Aralov A.V. // Nucleic Acids Res. 2023. V. 51. P. 2586–2601. https://doi.org/10.1093/nar/gkad100
- Schwechheimer C., Kuehn M.J. // Nat. Rev. Microbiol. 2015. V. 13. P. 605–619. https://doi.org/10.1038/nrmicro3525
- Gurung M., Moon D.C., Choi C.W., Lee J.H., Bae Y.C., Kim J., Lee Y.C., Seol S.Y., Cho D.T., Kim S.I. // PLoS One. 2011. V. 6. P. e27958. https://doi.org/10.1371/journal.pone.0027958
- Prados-Rosales R., Baena A., Martinez L.R., Luque-Garcia J., Kalscheuer R., Veeraraghavan U., Camara C., Nosanchuk J.D., Besra G.S., Chen B. // J. Clin. Invest. 2011. V. 121. P. 1471–1483.
- Mashburn L.M., Whiteley M. // Nature. 2005. V. 437. P. 422–425. https://doi.org/10.1038/nature03925
- Thuan Tong T., Mörgelin M., Forsgren A., Riesbeck K. // J. Infect. Dis. 2007. V. 195. P. 1661–1670. https://doi.org/10.1086/517611
- Kesty N.C., Mason K.M., Reedy M., Miller S.E., Kuehn M.J. // EMBO J. 2004. V. 23. P. 4538–4549. https://doi.org/10.1038/sj.emboj.7600471
- Tashiro Y., Yawata Y., Toyofuku M., Uchiyama H., Nomura N. // Microbes Environ. 2013. V. 28. P. 13–24. https://doi.org/10.1264/jsme2.ME12167
- Guerrero-Mandujano A., Hernández-Cortez C., Ibarra J.A., Castro-Escarpulli G. // Traffic. 2017. V. 18. P. 425–432. https://doi.org/10.1111/tra.12488
- Caruana J.C., Walper S.A. // Front. Microbiol. 2020. V. 11. P. 432. https://doi.org/10.3389/fmicb.2020.00432
- O’Donoghue E.J., Krachler A.M. // Cell. Microbiol. 2016. V. 18. P. 1508–1517. https://doi.org/10.1111/cmi.12655
- Kaparakis-Liaskos M., Ferrero R.L. // Nat. Rev. Immunol. 2015. V. 15. P. 375–387. https://doi.org/10.1038/nri3837
- Patten D.A., Hussein E., Davies S.P., Humphreys P.N., Collett A. // Microbiology. 2017. V. 163. P. 702–711. https://doi.org/10.1099/mic.0.000468
- Skerniškytė J., Karazijaitė E., Lučiūnaitė A., Sužiedėlienė E. // Pathogens. 2021. V. 10. P. 407. https://doi.org/10.3390/pathogens10040407
- Dorward D.W., Garon C.F., Judd R.C. // J. Bacteriol. 1989. V. 171. P. 2499–2505. https://doi.org/10.1128/jb.171.5.2499-2505.1989
- Alvarez-Erviti L., Seow Y., Yin H., Betts C., Lakhal S., Wood M.J. // Nat. Biotechnol. 2011. V. 29. P. 341– 345. https://doi.org/10.1038/nbt.1807
- Wood M., Yin H., McClorey G. // PLoS Genet. 2007. V. 3. P. e109. https://doi.org/10.1371/journal.pgen.0030109
- Biller S.J., Schubotz F., Roggensack S.E., Thompson A.W., Summons R.E., Chisholm S.W. // Science. 2014. V. 343. P. 183–186. https://doi.org/10.1126/science.1243457
- Sjöström A.E., Sandblad L., Uhlin B.E., Wai S.N. // Sci Rep. 2015. V. 5. P. 15329. https://doi.org/10.1038/srep15329
- Ghosal A., Upadhyaya B.B., Fritz J.V., Heintz-Buschart A., Desai M.S., Yusuf D., Huang D., Baumuratov A., Wang K., Galas D., Wilmes P. // Microbiology Open. 2015. V. 4. P. 252–266. https://doi.org/10.1002/mbo3.235
- Blenkiron C., Simonov D., Muthukaruppan A., Tsai P., Dauros P., Green S., Hong J., Print C.G., Swift S., Phillips A.R. // PLoS One. 2016. V. 11. P. e0160440. https://doi.org/10.1371/journal.pone.0160440
- Choi H.I., Kim M., Jeon J., Han J.K., Kim K.S. // Biochem. Biophys. Res. Commun. 2017. V. 490. P. 991–996. https://doi.org/10.1016/j.bbrc.2017.06.152
- Malabirade A., Habier J., Heintz-Buschart A., May P., Godet J., Halder R., Etheridge A., Galas D., Wilmes P., Fritz J.V. // Front Microbiol. 2018. V. 9. P. 2015. https://doi.org/10.3389/fmicb.2018.02015
- Choi J.S., Kim W., Suk S., Park H., Bak G., Yoon J., Lee Y. // RNA Biol. 2018. V. 15. P. 1319–1335. https://doi.org/10.1080/15476286.2018.1532252
- Resch U., Tsatsaronis J.A., Le Rhun A., Stübiger G., Rohde M., Kasvandik S., Holzmeister S., Tinnefeld P., Wai S.N., Charpentier E. // mBio. 2016. V. 7. P. e00207-16. https://doi.org/10.1128/mBio.00207-16
- Rodriguez B.V., Kuehn M.J. // Sci Rep. 2020. V. 10. P. 18293. https://doi.org/10.1038/s41598-020-75123-9
- Buck A.H., Coakley G., Simbari F., McSorley H.J., Quintana J.F., Le Bihan T., Kumar S., Abreu-Goodger C., Lear M., Harcus Y., Ceroni A., Babayan S.A., Blaxter M., Ivens A., Maizels R.M. // Nat Commun. 2014. V. 5. P. 5488. https://doi.org/10.1038/ncomms6488
- Koeppen K., Hampton T.H., Jarek M., Scharfe M., Gerber S.A., Mielcarz D.W., Demers E.G., Dolben E.L., Hammond J.H., Hogan D.A., Stanton B.A. // PLoS Pathog. 2016. V. 12. P. e1005672. https://doi.org/10.1371/journal.ppat.1005672
- Ho M.-H., Chen C.-H., Goodwin J.S., Wang B.-Y., Xie H. // PLoS One. 2015. V. 10. P. e0123448. https://doi.org/10.1371/journal.pone.0123448
- Joshi B., Singh B., Nadeem A., Askarian F., Wai S.N., Johannessen M., Hegstad K. // Front Mol Biosci. 2021. V. 7. P. 566207. https://doi.org/10.3389/fmolb.2020.566207
- Xu H., Li H., Sun B., Sun L. // Curr. Res. Microb. Sci. 2024. V. 7. P. 100318. https://doi.org/10.1016/j.crmicr.2024.100318
- Garcia-Silva M.R., Cabrera-Cabrera F., das Neves R.F., Souto-Padron T., de Souza W., Cayota A. // Biomed. Res Int. 2014. V. 2014. P. 305239. https://doi.org/10.1155/2014/305239
- Sahr T., Escoll P., Rusniok C., Bui S., Pehau-Arnaudet G., Lavieu G., Buchrieser C. // Nat. Commun. 2022. V. 13. P. 762. https://doi.org/10.1038/s41467-022-28454-x
- Fan L., Liu B., Wang Y., Tang B., Xu T., Fu J., Wang C., Liu Y., Ge L., Wei H. // Proc. Natl. Acad. Sci. USA. 2024. V. 121. P. e2413241121. https://doi.org/10.1073/pnas.2413241121
- Han E.-C., Choi S.-Y., Lee Y., Park J.-W., Hong S.-H., Lee H.-J. // FASEB J. 2019. V. 33. P. 13412. https://doi.org/10.1096/fj.201901575R
- Ha J.Y., Choi S.Y., Lee J.H., Hong S.H., Lee H.J. // Front Mol. Biosci. 2020. V. 7. P. 596366. https://doi.org/10.3389/fmolb.2020.596366
- Dauros-Singorenko P., Hong J., Swift S., Phillips A., Blenkiron C. // Front Mol. Biosci. 2020. V. 7. P. 580913. https://doi.org/10.3389/fmolb.2020.580913
- Moriano-Gutierrez S., Bongrand C., Essock-Burns T., Wu L., McFall-Ngai M.J., Ruby E.G. // PLoS Biol. 2020. V. 18. P. e3000934. https://doi.org/10.1371/journal.pbio.3000934
- Luna-Acosta A., Breitwieser M., Renault T., Thomas-Guyon H. // Mar. Pollut. Bull. 2017. V. 122. P. 5–16. https://doi.org/10.1016/j.marpolbul.2017.06.031
- Bloch S., Wegrzyn A., Wegrzyn G., Nejman-Falenczyk B. // Toxins (Basel). 2017. V. 9. P. 181. https://doi.org/10.3390/toxins9060181
- Mullany L.E., Herrick J.S., Wolff R.K., Slattery M.L. // PLoS One. 2016. V. 11. P. e0154177. https://doi.org/10.1371/journal.pone.0154177
- Kang S.-M., Choi J.-W., Lee Y., Hong S.-H., Lee H.-J. // Curr. Microbiol. 2013. V. 67. P. 609–613. https://doi.org/10.1007/s00284-013-0411-9
- Mao M.-Y., Yang Y.-M., Li K.-Z., Lei L., Li M., Yang Y., Tao X., Yin J.-X., Zhang R., Ma X.-R. // Front Microbiol. 2016. V. 7. P. 687. https://doi.org/10.3389/fmicb.2016.00687
- Coskun F.S., Srivastava S., Raj P., Dozmorov I., Belkaya S., Mehra S., Golden N.A., Bucsan A.N., Chapagain M.L., Wakeland E.K. // Front Microbiol. 2020. V. 11. P. 1631. https://doi.org/10.3389/fmicb.2020.01631
- Furuse Y., Finethy R., Saka H.A., Xet-Mull A.M., Sisk D.M., Smith K.L., Lee S., Coers J., Valdivia R.H., Tobin D.M., Cullen B.R. // PLoS One. 2014. V. 9. P. e106434. https://doi.org/10.1371/journal.pone.0106434
- Choi J.W., Kim S.C., Hong S.H., Lee H.J. // J. Dent. Res. 2017. V. 96. P. 458–466. https://doi.org/10.1177/0022034516685
- Gu H., Zhao C., Zhang T., Liang H., Wang X.M., Pan Y., Chen X., Zhao Q., Li D., Liu F., Zhang C.Y., Zen K. // Sci. Rep. 2017. V. 7. P. 2392. https://doi.org/10.1038/s41598-017-02669-1
- Cavanagh A.T., Wassarman K.M. // Annu. Rev. Microbiol. 2014. V. 68. P. 45–60. https://doi.org/10.1146/annurev-micro-092611-150135
补充文件



