Fungal Hydrophobins: Biosynthesis, Properties, Possibilities of Application in Biotechnology (Review)

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Abstract

The review summarizes current information about hydrophobins – low molecular weight proteins synthesized by filamentous fungi and which are one of the strongest cellular biosurfactants. The mechanism of biosynthesis of hydrophobins, the chemical structures and spectrum of its natural and synthetic isoforms, biological activity and role in the regulation of vital processes of producers are presented. The potential for using hydrophobins in biotechnology has been demonstrated.

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About the authors

E. V. Lopatukhin

Gause Institute of New Antibiotics

Author for correspondence.
Email: sadykova_09@mail.ru
Russian Federation, Moscow

Yu. A. Ihalainen

Lomonosov Moscow State University

Email: sadykova_09@mail.ru
Russian Federation, Moscow

N. N. Markelova

Gause Institute of New Antibiotics

Email: sadykova_09@mail.ru
Russian Federation, Moscow

A. E. Kuvarina

Gause Institute of New Antibiotics

Email: nastena.lysenko@mail.ru
Russian Federation, Moscow

V. S. Sadykova

Gause Institute of New Antibiotics

Email: sadykova_09@mail.ru
Russian Federation, Moscow

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2. Fig. 1. Primary structure of hydrophobins. Blue lines indicate the amino acid sequence, red numbers indicate the chain length, “Cys” circles indicate cysteines in the amino acid chain [10].

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