Nutritional and Possible Medicinal Value of Siberian Sturgeon (Acipenser baerii) and Sterlet (Acipenser ruthenus) Ovarian Fluid

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Chemical analysis of samples of ovarian fluid (OF), a secondary product of breeding of the two common in Russian aquaculture species of Acipenseridae family, was carried out in order to assess its nutritional and possible medicinal value. It has been figured out that the dominant organic component of OF of both species is a water-soluble or water-dispersible protein easily absorbed by the digestive tract. Proteomic analysis of the samples has shown that the main component of the protein fraction of OF is a highly nutritious protein vitellogenin. Amino acid analysis has shown that OF samples of both species satisfy the needs of an adult human in all essential amino acids. Eighty-five grams of dried sturgeon OF or 55 g of dried sterlet OF covers the daily requirement of an adult for vitamins C, B1, B2, B3 (PP) and B6, a number of macronutrients (Na, K, Ca, Mg) and micronutrients (Fe, Cu, Mn, Zn, Cr). Furthermore, Cu content is significantly higher in sturgeon OF, and Fe content is significantly higher in sterlet OF, which is partly confirmed by the relative content of Cu and Fe carrier proteins, ceruloplasmin and transferrin respectively. In addition, a number of proteins of physiological significance for fish were identified. The possible medicinal value of OF consists, among other things, in significant content of various antioxidant proteins in OF of both species. The use of OF as a food supplement could improve the profitability of sturgeon breeding by producing an additional valuable product, and would also expand the range of natural dietary supplements on the market.

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Sobre autores

M. Mikhailova

Institute of Biomedical Chemistry

Email: fireaxe@mail.ru
Rússia, Moscow, 119121

K. Zolotarev

Institute of Biomedical Chemistry

Autor responsável pela correspondência
Email: fireaxe@mail.ru
Rússia, Moscow, 119121

A. Mikhailov

Institute of Biomedical Chemistry

Email: fireaxe@mail.ru
Rússia, Moscow, 119121

V. Nakhod

Institute of Biomedical Chemistry

Email: fireaxe@mail.ru
Rússia, Moscow, 119121

V. Zgoda

Institute of Biomedical Chemistry

Email: fireaxe@mail.ru
Rússia, Moscow, 119121

E. Kharenko

Russian Federal Research Institute of Fisheries and Oceanography

Email: fireaxe@mail.ru
Rússia, Moscow, 105187

Bibliografia

  1. Lahnsteiner F., Weismann T., Patzner R. A. // Tissue Cell. 1997. V. 29. № 3. P. 305–314. https://doi.org/10.1016/s0040-8166(97)80006-7
  2. Zadmajid V., Myers J. N., Sørensen S. R., Ernest Butts I. A. // Theriogenology. 2019. V. 132. P. 144–152. https://doi.org/10.1016/j.theriogenology.2019.03.021
  3. Сытова М. В., Харенко Е. Н. // Рыбпром. 2007. № 3. С. 41–43.
  4. Ahmmed M.K., Ahmmed F., Carne A., Tian H. S., Bekhit A. E.-D.A. // Fish Roe Biochemistry, Products, and Safety. / Ed. A.E.-D.A. Bekhit. Amsterdam: Elsevier, 2022. P. 93–142. https://doi.org/10.1016/B978-0-12-819893-3.00005-9
  5. Харенко Е. Н., Дмитриева Е. А., Сытова М. В. // Рыбное хозяйство. 2011. № 3. С. 79–85.
  6. Lam M., Khoshkhat P., Chamani M., Shahsavari S., Dorkoosh F. A., Rajabi A., Maniruzzaman M., Nokhodchi A. // J. Drug Deliv. Sci. Tech. 2022. V. 67. P. 102985. https://doi.org/10.1016/j.jddst.2021.102985
  7. Дмитриева Е.А., Харенко Е. Н., Сытова М. В. // Хранение и переработка сельхозсырья. 2012. № 3. С. 12–15.
  8. Mikhailova M.V., Zolotarev K. V., Mikhailov A. N., Sanzhakov M. A., Farafonova T. E. // International Journal of Management and Humanities. 2019. V. 4. № 4. P. 1–5. https://doi.org/10.35940/ijmh.C0442.124419
  9. Heudi O., Kilinç T., Fontannaz P. // J. Chromatogr. A. 2005. V. 1070. № 1–2. P. 49–56. https://doi.org/10.1016/j.chroma.2005.02.033
  10. Mikhailova M., Zolotarev K., Nakhod V., Farafonova T., Mikhailov A. // E3S Web of Conferences. 2022. V. 363. P. 03017. https://doi.org/10.1051/e3sconf/202236303017
  11. Капица И. Г., Казиева Л. Ш., Вавилов Н. Э., Згода В. Г., Копылов А. Т., Медведев А. Е., Бунеева О. А. // Биомедицинская химия. 2023. Т. 69. № 1. С. 46–54. https://doi.org/10.18097/PBMC20236901046
  12. Yousefi M., Rahimi-Nasrabadi M., Pourmortazavi S. M., Wysokowski M., Jesionowski T., Ehrlich H., Mirsadeghi S. // TrAC Trends Anal. Chem. 2019. V. 118. P. 182–193. https://doi.org/10.1016/j.trac.2019.05.038
  13. Pillai R. R., Kurpad A. V. // Br. J. Nutr. 2012. V. 108. Suppl 2. P. S44–S49. https://doi.org/10.1017/S0007114512002401
  14. Das P., Sahoo L., Das S. P., Bit A., Joshi C. G., Kushwaha B. et al. // Front. Genet. 2020. V. 11. P. 386. https://doi.org/10.3389/fgene.2020.00386
  15. Janeway C. A. Jr., Travers P. Immunobiology: The Immune System in Health and Disease. 5th ed. N.Y.: Garland Science, 2001. 450 p.
  16. Johnson S. L., Villarroel M., Rosengrave P., Carne A., Kleffmann T., Lokman P. M., Gemmell N. J. // PLoS One. 2014. V. 9. № 8. P. e104155. https://doi.org/10.1371/journal.pone.0104155
  17. Nynca J., Arnold G. J., Fröhlich T., Ciereszko A. // Reprod. Fertil. Dev. 2015. V. 27. № 3. P. 504–512. https://doi.org/10.1071/RD13224
  18. Nynca J., Zarski D., Fröhlich T., Köster M., Bobe J., Ciereszko A. // Aquac. 2022. V. 548. Part 2. P. 737656. https://doi.org/10.1016/j.aquaculture.2021.737656
  19. Russell S., Hayes M. A., Lumsden J. S. // Fish Shellfish Immunol. 2009. V. 26. № 1. P. 154–163. https://doi.org/10.1016/j.fsi.2008.03.001
  20. Xu Z., Zan H., Pone E. J., Mai T., Casali P. // Nat. Rev. Immunol. 2012. V. 12. № 7. P. 517–531. https://doi.org/10.1038/nri3216
  21. McDonald K., Glezeva N., Collier P., O’Reilly J., O’Connell E., Tea I. et al. // Sci. Rep. 2020. V. 10. № 1. P. 7507. https://doi.org/10.1038/s41598-020-64558-4
  22. Gettins P. G. W. // Chem. Rev. 2002. V. 102. № 12. P. 4751–4804. https://doi.org/10.1021/cr010170+
  23. Fletcher G. L., Hew C. L., Davies P. L. // Annu. Rev. Physiol. 2001. V. 63. P. 359–390. https://doi.org/10.1146/annurev.physiol.63.1.359
  24. Fang L., Hu X., Cui L., Lv P., Ma X., Ye Y. // J. Assist. Reprod. Genet. V. 36. № 6. P. 1101–1107. https://doi.org/10.1007/s10815-019-01454-5
  25. Grummer R. R., Carroll D. J. // J. Anim. Sci. 1988. V. 66. № 12. P. 3160–3173. https://doi.org/10.2527/jas1988.66123160x
  26. Robinson R. // PLoS Biol. 2008. V. 6. № 3. P. e77. https://doi.org/10.1371/journal.pbio.0060077
  27. Crichton R. R., Charloteaux-Wauters M. // Eur. J. Biochem. 1987. V. 164. № 3. P. 485–506. https://doi.org/10.1111/j.1432-1033.1987.tb11155.x
  28. Hellman N. E., Gitlin J. D. // Annu. Rev. Nutr. 2002. V. 22. P. 439–458. https://doi.org/10.1146/annurev.nutr.22.012502.114457
  29. Mills G. C. // J. Biol. Chem. 1957. V. 229. № 1. P. 189–197. https://doi.org/10.1016/S0021-9258(18)70608-X
  30. Rhee S. G., Kil I. S. // Annu. Rev. Biochem. 2017. V. 86. P. 749–775. https://doi.org/10.1146/annurev-biochem-060815-014431
  31. Mostert V. // Arch. Biochem. Biophys. 2000. V. 376. № 2. P. 433–438. https://doi.org/10.1006/abbi.2000.1735
  32. Holmgren A. // J. Biol. Chem. 1989. V. 264. № 24. P. 13963–13966. https://doi.org/10.1016/S0021-9258(18)71625-6
  33. Mikhailova M., Zolotarev K., Mikhailov A., Lapin A., Nakhod V. // E3S Web of Conferences. 2023. V. 381. P. 01075. https://doi.org/10.1051/e3sconf/202338101075
  34. Михайлова М. В., Беляева Н. Ф., Козлова Н. И., Золотарев К. В. , Михайлов А. Н., Подушка С. Б. // Biomedical Chemistry: Research and Methods. 2018. Т. 1. № 2. С. e00011. https://doi.org/10.18097/BMCRM00011

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2. Fig. 1. Relative content (expressed as the intensity of the signal of the mass spectrometric detector) of proteins or their groups characterizing the antioxidant activity of the studied species in terms of their nutritional and potential therapeutic and prophylactic value: a — vitellogenin (nutritional protein); b — transferrin (Fe carrier); c — ceruloplasmin (Cu carrier); d — antioxidant proteins (in total). * A significantly higher value compared to the corresponding one for a given protein/group, according to the Mann–Whitney U-test at p < 0.05 (n = 5).

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