Synthesis of new fused 3(4)-substituted 11-furylthieno[3,2-d]pyrimidine derivatives

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Аннотация

A method was developed for the synthesis of new fused 3-alkyl-substituted derivatives of thieno[3,2- d ]pyrimidin-4(3 H )-ones based on 11-(2-furyl)-8,8-dimethyl-7,10-dihydro-8 H -pyrano[3′′,4′′:5′,6′]pyrido[3′,2′:4,5]-thieno[3,2- d ]pyrimidin-4(3 H )-one via nucleophilic substitution in the pyrimidine ring. A series of fused 4-amino-substituted 11-furylthieno[3,2- d ]pyrimidine derivatives was also synthesized from the corresponding 4-chloro derivative.

Авторлар туралы

V. Dabaeva

Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Science of the Republic of Armenia

Email: valyadabayeva@mail.ru

M. Baghdasaryan

Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Science of the Republic of Armenia

I. Barkhudaryants

Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Science of the Republic of Armenia

E. Paronikyan

Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Science of the Republic of Armenia

Sh. Dashyan

Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Science of the Republic of Armenia

Әдебиет тізімі

  1. Wójcicka A., Redzicka A. // Pharmaceuticals. 2021. Vol. 14. N 4. P. 354. doi: 10.3390/ph14040354
  2. Pavlinac I. B., Zlatić K., Persoons L., Daelemans D., Banjanac M., Radovanović V., Butković K., Kralj M., Hranjec M. // Molecules. 2023. Vol. 28. P. 34. doi: 10.3390/molecules28010034
  3. Aronson J.K. In: Meyler's Side Effects of Drugs. Elsevier, 2016. Vol. 7. P. 99. doi: 10.1016/B978-0-444-53717-1.00234-1
  4. Aronson J.K. In: Meyler's Side Effects of Drugs, Elsevier, 2016. Vol. 7. P. 793. doi: 10.1016/B978-0-444-53717-1.01296-8
  5. Kumar A., Kumar Bhagat K., Kumar Singh A., Singh H., Angre T., Verma A., Khalilullah H., Jaremko M., Emwase A.-H., Kumar P. // RSC Adv. 2023. Vol. 13. P. 6872. doi: 10.1039/D3RA00056G
  6. Huerta-García C.S., Pérez D.J., Velázquez-Martínez C.A., Tabatabaei Dakhili S.A., Romo-Mancillas A., Castillo R., Hernández-Campos A. // Pharmaceuticals. 2022. Vol. 15. N 3. P. 283. doi: 10.3390/ph15030283
  7. Al-Trawneh S.A., Tarawneh A.H., Gadetskaya A.V., Seo E.-J., Al-Ta'ani M.R., Al-Taweel S.A., El-Abadelah M.M. // Acta Chim. Slov. 2021. Vol. 68. P. 458. doi: 10.17344/acsi.2020.6609
  8. Dashyan Sh.Sh., Babaev E.V., Paronikyan E.G., Ayvazyan A.G., Paronikyan R.G., Hunanyan L.S. // Molecules. 2022. Vol. 27. N 11. P. 3380. doi: 10.3390/molecules27113380
  9. Loidreau Y., Nourrisson M.-R., Fruit C., Corbière C., Marchand P., Besson T. // Pharmaceuticals. 2020. Vol. 13. N 9. P. 202. doi: 10.3390/ph13090202
  10. Дабаева В.В., Багдасарян М.Р., Дашян Ш.Ш., Джагацпанян И.А., Назарян И.М., Акопян А.Г., Пароникян Р.Г. // Хим.-фарм. ж. 2019. Т. 52. № 10. С. 28
  11. Dabaeva V.V., Bagdasaryan M.R., Dashyan Sh.Sh., Dzhagatspanyan I.A., Nazaryan I.M., Akopyan A.G., Paronikyan R.G. // Pharm. Chem. J. 2019. Vol. 52. P. 844. doi: 10.1007/s11094-019-1912-z
  12. Дабаева В.В., Багдасарян М.Р., Пароникян Е.Г., Бархударянц И.М., Паносян Г.А., Степанян Г.М., Дашян Ш.Ш. // ЖОрХ. 2023. Т. 59. Вып. 1. С. 119
  13. Dabayeva V.V., Baghdasaryan M.R., Paronikyan E.G., Barkhudaryants I.M., Panosyan H.A., Stepanyan H.M., Dashyan Sh.Sh. // Russ. J. Organic Chem. 2023. Vol. 59. P. 78. doi: 10.1134/S1070428023010086
  14. Дабаева В.В., Багдасарян М.Р., Пароникян Е.Г., Тамазян Р.А., Айвазян А.Г., Дашян Ш.Ш. // ЖОХ. 2019. Т. 89. Вып. 12. С. 1842
  15. Dabaeva V.V., Baghdasaryan M.R., Paronikyan E.G., Tamazyan R.A., Ayvazyan A.G., Dashyan Sh.Sh. // Russ. J. Gen. Chem. 2019. Vol. 89. P. 2364. doi: 10.1134/S1070363219120065

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